Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroform SCHEMBL10585238 | 0.96 | PDE7A (0.70) | PDE7APTGS2 | |
| SCHEMBL9670259 | 0.87 | PDE7A (0.76) | PDE7A | |
| SCHEMBL9671578 | 0.87 | PDE7A (0.76) | PDE7APTGS2 | |
| SCHEMBL9671403 | 0.86 | PDE7A (1.00) | PDE7APTGS2 | |
| SCHEMBL9670297 | 0.82 | PDE7A (0.78) | PDE7APTGS2 | |
| SCHEMBL9381672 | 0.81 | PDE7A (0.80) | PDE7APTGS2 | |
| SCHEMBL9672681 | 0.79 | PDE7A (0.85) | PDE7APTGS2 | |
| SCHEMBL3337074 | 0.78 | PDE7A (0.63) | PDE7APTGS2 | |
| SCHEMBL9672666 | 0.77 | PDE7A (0.77) | PDE7APTGS2 | |
| SCHEMBL9823344 | 0.77 | PDE7A (0.44) | PDE7APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276825-B1 | 4 (3H)-QUINAZOLINONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-09-09 | — | — | EP | disclosed |
| EP-0276826-B1 | 2-ALKYLSULFINYL-4 (3H)-QUINAZOLINONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-12-27 | — | — | EP | disclosed |
| US-5008266-A | Antiulcer agent | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-04-16 | — | — | US | disclosed |
| US-4861780-A | 4(3H)-quinazolinone derivatives and pharmaceutical compositions | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-08-29 | — | — | US | disclosed |
| EP-0276825-A1 | 4 (3H)-Quinazolinone derivatives, processes for their preparation and pharmaceutical compositions | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1988-08-03 | — | — | EP | disclosed |
| EP-0276826-A1 | 2-Alkylsulfinyl-4 (3H)-quinazolinone derivatives, processes for their preparation and pharmaceutical compositions | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1988-08-03 | — | — | EP | disclosed |