Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9669912 | 0.95 | KDM4E (0.47) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9670553 | 0.87 | KDM4E (0.63) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10912460 | 0.87 | KDM4E (0.46) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10759404 | 0.85 | KDM4E (0.47) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10886385 | 0.85 | ALDH1A1 (0.48) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9866071 | 0.84 | KDM4E (0.60) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10646730 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9669720 | 0.84 | KDM4E (0.44) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9670034 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9670733 | 0.84 | KDM4E (0.54) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274033-B1 | PROCESS FOR THE PREPARATION OF QUINOLINECARBOXYLIC ACIDS | BAYER AG (DE) | 1992-03-11 | — | — | EP | disclosed |
| EP-0274033-A1 | Process for the preparation of quinolinecarboxylic acids | BAYER AG (DE) | 1988-07-13 | — | — | EP | disclosed |
| EP-0230274-A2 | Derivatives of 7-(azabicycloalkyl)-quinoloncarboxylic acid and -naphthyridoncarboxylic acid | BAYER AG (DE) | 1987-07-29 | — | — | EP | disclosed |