Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | TOP2A | P11388 | 6/20 | 0.46 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866014 | 0.95 | DPP4 (0.57) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9670589 | 0.93 | DPP4 (0.59) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9670607 | 0.88 | DPP4 (0.47) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9837624 | 0.88 | LMNA (0.62) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9686661 | 0.87 | DPP4 (0.46) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9686415 | 0.87 | DPP4 (0.46) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL5141828 | 0.85 | DPP4 (0.45) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9672074 | 0.83 | DPP4 (0.61) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9838619 | 0.82 | DPP4 (0.56) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL10874660 | 0.81 | DPP4 (0.63) | DPP4CHRM2DRD1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159174-B1 | SUBSTITUTED NAPHTHYRIDINE-, QUINOLINE- AND BENZOXAZINE- CARBOXYLIC ACIDS AS ANTIBACTERIAL AGENTS AND PROCESSES FOR THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1991-10-23 | — | — | EP | claimed |
| US-4571396-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1986-02-18 | — | — | US | claimed |
| EP-0159174-A2 | Substituted naphthyridine-, quinoline- and benzoxazine- carboxylic acids as antibacterial agents and processes for their production | WARNER-LAMBERT COMPANY (US) | 1985-10-23 | — | — | EP | claimed |
| EP-0274033-B1 | PROCESS FOR THE PREPARATION OF QUINOLINECARBOXYLIC ACIDS | BAYER AG (DE) | 1992-03-11 | — | — | EP | disclosed |
| EP-0159174-B1 | SUBSTITUTED NAPHTHYRIDINE-, QUINOLINE- AND BENZOXAZINE- CARBOXYLIC ACIDS AS ANTIBACTERIAL AGENTS AND PROCESSES FOR THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1991-10-23 | — | — | EP | disclosed |
| EP-0274033-A1 | Process for the preparation of quinolinecarboxylic acids | BAYER AG (DE) | 1988-07-13 | — | — | EP | disclosed |
| US-4571396-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1986-02-18 | — | — | US | disclosed |
| EP-0159174-A2 | Substituted naphthyridine-, quinoline- and benzoxazine- carboxylic acids as antibacterial agents and processes for their production | WARNER-LAMBERT COMPANY (US) | 1985-10-23 | — | — | EP | disclosed |