Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11206285 | 0.86 | IDO1 (0.53) | IDO1RAB9AHTR2AAKR1C3HTT | |
| SCHEMBL11396185 | 0.85 | IDO1 (0.53) | IDO1RAB9AHTR2AAKR1C3HTT | |
| SCHEMBL10500167 | 0.83 | IDO1 (0.54) | IDO1RAB9AHTR2AAKR1C3HTT | |
| SCHEMBL9782567 | 0.82 | IDO1 (0.56) | IDO1RAB9AHTR2AAKR1C3HTT | |
| SCHEMBL9820376 | 0.82 | IDO1 (0.56) | IDO1RAB9AHTR2AAKR1C3HTT | |
| SCHEMBL28203842 | 0.82 | IDO1 (0.53) | IDO1RAB9AHTR2AAKR1C3HTT | |
| SCHEMBL6400055 | 0.82 | IDO1 (0.53) | IDO1RAB9AHTR2AAKR1C3HTT | |
| SCHEMBL11383886 | 0.82 | IDO1 (0.53) | IDO1RAB9AHTR2AAKR1C3HTT | |
| SCHEMBL5724349 | 0.82 | HTR2A (0.55) | IDO1RAB9AHTR2AAKR1C3HTT | |
| SCHEMBL8247254 | 0.81 | HTR2A (0.60) | IDO1RAB9AHTR2AAKR1C3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237027-B1 | 6-(DISUBSTITUTED AMINO) CARBAPENAM COMPOUNDS | Sanraku Incorporated (JP) | 1992-06-10 | — | — | EP | disclosed |
| US-4996314-A | 6-(disubstituted amino)carbapenem compounds | SANRAKU INCORPORATED (JP) | 1991-02-26 | — | — | US | disclosed |
| US-4812563-A | ANTIBIOTICS | SANRAKU INCORPORATED (JP) | 1989-03-14 | — | — | US | disclosed |
| EP-0237027-A2 | 6-(Disubstituted amino) carbapenam compounds | Sanraku Incorporated (JP) | 1987-09-16 | — | — | EP | disclosed |
| EP-0105227-A1 | Process for producing beta-lactam compounds, and intermediates useful for their production | Sanraku Incorporated (JP) | 1984-04-11 | — | — | EP | disclosed |
| EP-0005348-B1 | CARBAPENEM DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1982-09-22 | — | — | EP | disclosed |
| EP-0040408-A1 | Beta-lactam compounds and process for production thereof | SANRAKU-OCEAN CO., LTD. (JP) | 1981-11-25 | — | — | EP | disclosed |