Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820376 | 0.87 | IDO1 (0.56) | IDO1RAB9AHTR2AAKR1C3HTT | |
| SCHEMBL9782567 | 0.87 | IDO1 (0.56) | IDO1RAB9AHTR2AAKR1C3HTT | |
| SCHEMBL9670638 | 0.86 | IDO1 (0.56) | IDO1RAB9AHTR2AAKR1C3HTT | |
| SCHEMBL29171050 | 0.84 | HTR2A (0.59) | IDO1RAB9AHTR2AAKR1C3HTT | |
| SCHEMBL11658704 | 0.83 | IDO1 (0.51) | IDO1RAB9AHTR2AAKR1C3HTT | |
| SCHEMBL8247254 | 0.82 | HTR2A (0.60) | IDO1RAB9AHTR2AAKR1C3HTT | |
| SCHEMBL6481479 | 0.81 | IDO1 (0.58) | IDO1RAB9AHTR2AAKR1C3HTT | |
| SCHEMBL37664 | 0.81 | HTR2A (0.62) | IDO1RAB9AHTR2AAKR1C3HTT | |
| SCHEMBL11381642 | 0.81 | TGM2 (0.55) | IDO1RAB9AHTR2AAKR1C3 | |
| SCHEMBL11396185 | 0.80 | IDO1 (0.53) | IDO1RAB9AHTR2AAKR1C3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0089139-A2 | Antibiotics, their preparation and use | BEECHAM GROUP PLC (GB) | 1983-09-21 | — | — | EP | disclosed |