Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670684 | 1.00 | CYP1A2 (0.52) | CYP1A2CYP2C9CYP2C19SMN1; SMN2POLB | |
| SCHEMBL9672240 | 0.87 | SMN1; SMN2 (0.42) | CYP1A2CYP2C9CYP2C19SMN1; SMN2POLB | |
| SCHEMBL9672244 | 0.87 | SMN1; SMN2 (0.42) | CYP1A2CYP2C9CYP2C19SMN1; SMN2POLB | |
| SCHEMBL9673200 | 0.85 | POLB (0.60) | CYP1A2CYP2C9CYP2C19SMN1; SMN2POLB | |
| SCHEMBL9673192 | 0.85 | POLB (0.60) | CYP1A2CYP2C9CYP2C19SMN1; SMN2POLB | |
| SCHEMBL9672878 | 0.85 | SMN1; SMN2 (0.51) | CYP1A2CYP2C9CYP2C19SMN1; SMN2GAA | |
| SCHEMBL9671187 | 0.85 | SMN1; SMN2 (0.51) | CYP1A2CYP2C9CYP2C19SMN1; SMN2GAA | |
| SCHEMBL9671184 | 0.85 | SMN1; SMN2 (0.51) | CYP1A2CYP2C9CYP2C19SMN1; SMN2GAA | |
| SCHEMBL9262039 | 0.84 | SMN1; SMN2 (0.50) | CYP1A2CYP2C9CYP2C19SMN1; SMN2GAA | |
| SCHEMBL9674507 | 0.84 | SMN1; SMN2 (0.50) | CYP1A2CYP2C9CYP2C19SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361827-B1 | PYRAZOLE COMPOUNDS, METHOD FOR PRODUCTION THEREOF, USE THEREOF AND INTERMEDIATES FOR PRODUCTION THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1992-12-16 | — | — | EP | claimed |