Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9672244 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2CYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL9670684 | 0.87 | CYP1A2 (0.52) | SMN1; SMN2CYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL9670677 | 0.87 | CYP1A2 (0.52) | SMN1; SMN2CYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL9671184 | 0.86 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL9671187 | 0.86 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL9672878 | 0.86 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL9262039 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL9674507 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL9262044 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL9674546 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP1A2CYP2C9CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361827-B1 | PYRAZOLE COMPOUNDS, METHOD FOR PRODUCTION THEREOF, USE THEREOF AND INTERMEDIATES FOR PRODUCTION THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1992-12-16 | — | — | EP | claimed |