Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.55 |
| ▸ | HRH1 | P35367 | 2/20 | 0.55 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29784674 | 0.90 | AOC3 (0.56) | HTR2AHRH1AOC3SLC6A4 | |
| SCHEMBL2279687 | 0.90 | AOC3 (0.56) | HTR2AHRH1AOC3UTS2R | |
| SCHEMBL5610068 | 0.90 | HTR2A (0.71) | HTR2AHRH1AOC3CHRM2ADRA2B | |
| SCHEMBL11433536 | 0.83 | HTR2A (0.53) | HTR2AHRH1UTS2RALDH1A1 | |
| SCHEMBL11390029 | 0.83 | HTR2A (0.53) | HTR2AHRH1AOC3HPGDUTS2R | |
| SCHEMBL5463519 | 0.81 | UTS2R (0.46) | HTR2AHRH1UTS2R | |
| Hydrochloric Acid SCHEMBL14775166 | 0.80 | POLB (0.52) | HTR2AHRH1SLC6A4ALDH1A1 | |
| SCHEMBL6829520 | 0.79 | AOC3 (0.58) | HTR2AHRH1AOC3SLC6A4 | |
| SCHEMBL188905 | 0.79 | HTR2A (0.42) | HTR2AHRH1AOC3ALDH1A1RIPK1 | |
| SCHEMBL4731821 | 0.79 | HTR2A (0.42) | HTR2AHRH1AOC3RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093370-A | Useful prior to insertion of tracheotomy tube or discission | TOBISHI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 1992-03-03 | — | — | US | disclosed |