Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31572076 | 1.00 | AOC3 (0.58) | AOC3TAAR1MEN1KMT2AHTR2A | |
| SCHEMBL29784674 | 0.91 | AOC3 (0.56) | AOC3TAAR1MEN1KMT2AHTR2A | |
| SCHEMBL11388130 | 0.90 | AOC3 (0.49) | AOC3TAAR1MEN1KMT2AHTR2A | |
| Mandelic Acid SCHEMBL31572074 | 0.84 | LMNA (0.49) | AOC3HTR2AHRH1SLC6A4SLC6A3 | |
| SCHEMBL5463519 | 0.82 | UTS2R (0.46) | HTR2AHRH1 | |
| SCHEMBL4733883 | 0.81 | CHRM2 (0.49) | TAAR1MEN1KMT2AHTR2AHRH1 | |
| SCHEMBL5454333 | 0.81 | AOC3 (0.58) | AOC3HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL188905 | 0.81 | HTR2A (0.42) | AOC3TAAR1HTR2AHRH1 | |
| SCHEMBL4731821 | 0.81 | HTR2A (0.42) | AOC3HTR2AHRH1 | |
| SCHEMBL1205131 | 0.80 | AOC3 (0.72) | AOC3TAAR1MEN1KMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119912424-A | Crystal forms of (R) -3- [ (benzodioxol-4-yl) oxy ] -N, N-dimethyl-3- (4-fluorophenyl) propylamine oxalate and preparation method and application thereof | 江苏恩华药业股份有限公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-105777706-B | A kind of 3- [(benzo [d] [1,3] dioxolanes -4- base)-oxygroup] -3- arylprop aminated compounds and its application | 江苏恩华药业股份有限公司 | 2019-08-23 | — | — | CN | disclosed |
| US-10093644-B2 | 3-[(Benzo[D][1,3]dioxolan-4-yl)-oxy]-3-arylpropylamine type compounds and applications thereof | NHWA PHARMA. CORPORATION (CN) | 2018-10-09 | — | — | US | disclosed |
| US-20170369466-A1 | 3-[(BENZO[D][1,3]DIOXOLAN-4-YL)-OXY]-3-ARYLPROPYLAMINE TYPE COMPOUNDS AND APPLICATIONS THEREOF | NHWA PHARMA. CORPORATION (CN) | 2017-12-28 | — | — | US | disclosed |
| WO-2004043921-A1 | NOVEL PROCESS FOR THE PREPARATION OF 4-ARYL-3-HYDROXYMETHYL-1-METHYLPIPERIDINES. | NATCO PHARMA LIMITED (IN) | 2004-05-27 | — | — | WO | disclosed |
| EP-0399504-B1 | Aryloxyphenylpropylamines their preparation and use | NOVO NORDISK AS (DK) | 1995-05-03 | — | — | EP | disclosed |
| US-5310756-A | Aryloxyphenylpropylamines and their calcium overload blocking compositions and methods of use | NOVO NORDISK A/S (DK) | 1994-05-10 | — | — | US | disclosed |
| US-5145870-A | Treating calcium overload in brain cells, anoxia, migraine, ischemia, epilepsy, neurodegenerative diseases | NOVO NORDISK A/S (DK) | 1992-09-08 | — | — | US | disclosed |
| EP-0399504-A2 | Aryloxyphenylpropylamines their preparation and use | NOVO NORDISK A/S (DK) | 1990-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10093644-B2 | 3-[(Benzo[D][1,3]dioxolan-4-yl)-oxy]-3-arylpropylamine type compounds and applications thereof | TPH1, MAOA, MAOB | AOC3 35/4885TAAR1 98/4885MEN1 4658/4885 |
| US-20170369466-A1 | 3-[(BENZO[D][1,3]DIOXOLAN-4-YL)-OXY]-3-ARYLPROPYLAMINE TYPE COMPOUNDS AND APPLICATIONS THEREOF | TPH1, MAOA, MAOB | AOC3 35/4885TAAR1 98/4885MEN1 4658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.