Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8359975 | 0.78 | MAPT (0.52) | KIF11EPHX2ALDH1A1HPGDMAPT | |
| SCHEMBL5499496 | 0.75 | EPHX2 (0.54) | KIF11EPHX2ALDH1A1HPGDMAPT | |
| SCHEMBL21339362 | 0.75 | ALDH1A1 (0.49) | KIF11EPHX2ALDH1A1HPGDMAPT | |
| SCHEMBL7717477 | 0.73 | EPHX2 (0.56) | KIF11EPHX2ALDH1A1HPGDMAPT | |
| SCHEMBL7717474 | 0.73 | EPHX2 (0.56) | KIF11EPHX2ALDH1A1HPGDMAPT | |
| SCHEMBL6698062 | 0.72 | TDP1 (0.52) | ALDH1A1CA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL7704859 | 0.72 | EPHX2 (0.54) | KIF11EPHX2ALDH1A1HPGDMAPT | |
| Hydrochloric Acid SCHEMBL7704862 | 0.72 | EPHX2 (0.54) | KIF11EPHX2ALDH1A1HPGDMAPT | |
| SCHEMBL11205128 | 0.71 | ALDH1A1 (0.58) | KIF11EPHX2ALDH1A1HPGDMAPT | |
| SCHEMBL11205131 | 0.71 | ALDH1A1 (0.58) | KIF11EPHX2ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375510-B1 | 2-IMINO-6-POLYFLUOROALCOXY-BENZOTHIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | RHONE-POULENC SANTE (FR) | 1992-11-11 | — | — | EP | disclosed |
| EP-0375510-A1 | 2-Imino-6-polyfluoroalcoxy-benzothiazole derivatives, process for their preparation and medicaments containing them | RHONE-POULENC SANTE (FR) | 1990-06-27 | — | — | EP | disclosed |