Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.51 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | OXTR | P30559 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GPR183 | P32249 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2186062 | 0.84 | NNMT (0.64) | NNMTMAPTKDM4EMEN1KMT2A | |
| SCHEMBL30543017 | 0.84 | NNMT (0.64) | NNMTMAPTKDM4EMEN1KMT2A | |
| SCHEMBL1535155 | 0.83 | NNMT (0.62) | NNMTMAPTKDM4EMEN1KMT2A | |
| SCHEMBL29786256 | 0.83 | NNMT (0.62) | NNMTMAPTKDM4EMEN1KMT2A | |
| SCHEMBL21741497 | 0.83 | NNMT (0.62) | NNMTMAPTKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30461874 | 0.83 | NNMT (0.62) | NNMTMAPTKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9753848 | 0.81 | NNMT (0.65) | NNMTMAPTKDM4EMEN1KMT2A | |
| Bromide SCHEMBL6116910 | 0.81 | NNMT (0.60) | NNMTMAPTKDM4EMEN1KMT2A | |
| SCHEMBL2493127 | 0.80 | NNMT (0.68) | NNMTMAPTKDM4EMEN1KMT2A | |
| SCHEMBL2154730 | 0.80 | NNMT (0.68) | NNMTMAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506729-A1 | PHARMACEUTICALLY ACTIVE OXAZOLE COMPOUNDS | Beecham Group p.l.c. (GB) | 1992-10-07 | — | — | EP | disclosed |
| WO-1991009856-A1 | PHARMACEUTICALLY ACTIVE OXAZOLE COMPOUNDS | BEECHAM GROUP PLC (GB) | 1991-07-11 | — | — | WO | disclosed |