Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | MARK3 | P27448 | 1/20 | 0.38 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.38 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520892 | 0.79 | L3MBTL1 (0.70) | L3MBTL1PDE10AEPHX1ACHEHTR6 | |
| SCHEMBL10088115 | 0.79 | L3MBTL1 (0.74) | L3MBTL1PDE10AEPHX1ACHEHTR6 | |
| SCHEMBL5740608 | 0.79 | L3MBTL1 (1.00) | L3MBTL1PDE10AEPHX1ACHEHTR6 | |
| SCHEMBL9647061 | 0.79 | L3MBTL1 (0.44) | L3MBTL1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL16398958 | 0.77 | L3MBTL1 (0.71) | L3MBTL1PDE10AEPHX1ACHEHTR6 | |
| SCHEMBL29277143 | 0.76 | L3MBTL1 (0.70) | L3MBTL1PDE10AEPHX1ACHEHTR6 | |
| SCHEMBL24729176 | 0.76 | L3MBTL1 (0.66) | L3MBTL1PDE10AEPHX1ACHEHTR6 | |
| SCHEMBL22651784 | 0.76 | L3MBTL1 (0.70) | L3MBTL1PDE10AEPHX1ACHEHTR6 | |
| SCHEMBL30721514 | 0.76 | L3MBTL1 (0.66) | L3MBTL1PDE10AEPHX1ACHEHTR6 | |
| SCHEMBL4109142 | 0.76 | L3MBTL1 (0.66) | L3MBTL1PDE10AEPHX1ACHEHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284174-B1 | THERAPEUTIC PREPARATIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-29 | — | — | EP | disclosed |