Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.64 |
| ▸ | DRD1 | P21728 | 1/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.64 |
| ▸ | DRD3 | P35462 | 1/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670538 | 0.93 | KCNH2 (0.72) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11633241 | 0.92 | KCNH2 (0.72) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11693699 | 0.87 | KCNH2 (0.65) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9670343 | 0.86 | KCNH2 (0.65) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| Hydrochloric Acid SCHEMBL11696864 | 0.85 | KCNH2 (0.63) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9671564 | 0.84 | KCNH2 (0.68) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9670944 | 0.84 | KCNH2 (0.68) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9671701 | 0.84 | KCNH2 (0.68) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9670241 | 0.84 | KCNH2 (0.68) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL12156482 | 0.83 | KCNH2 (0.60) | KCNH2CHRM2HTR1AADRA2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093370-A | Useful prior to insertion of tracheotomy tube or discission | TOBISHI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 1992-03-03 | — | — | US | disclosed |