Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA4 | P22748 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29848505 | 1.00 | SNCA (0.51) | SNCAMAPTALDH1A1LMNATDP1 | |
| SCHEMBL20982602 | 0.88 | MAPT (0.66) | SNCAMAPTALDH1A1LMNATDP1 | |
| SCHEMBL11209297 | 0.82 | MAPT (0.57) | MAPTALDH1A1LMNATDP1MEN1 | |
| SCHEMBL11420051 | 0.82 | MAPT (0.62) | MAPTALDH1A1LMNATDP1MEN1 | |
| SCHEMBL21177279 | 0.82 | SNCA (0.48) | SNCAMAPTALDH1A1LMNATDP1 | |
| SCHEMBL11548169 | 0.81 | MAPT (0.60) | MAPTALDH1A1LMNATDP1MEN1 | |
| SCHEMBL11545117 | 0.81 | MAPT (0.60) | MAPTALDH1A1LMNATDP1MEN1 | |
| SCHEMBL11549858 | 0.80 | MAPT (0.59) | MAPTALDH1A1LMNATDP1MEN1 | |
| SCHEMBL11545962 | 0.80 | MAPT (0.59) | MAPTALDH1A1LMNATDP1MEN1 | |
| SCHEMBL6325046 | 0.80 | MAPT (0.54) | MAPTALDH1A1LMNATDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11439640-B2 | Pharmaceutical composition comprising substance inhibiting enzymatic activity of peroxiredoxin 2 as effective ingredient for treatment of colorectal cancer | EWHA University—Industry Collaboration Foundation (KR) | 2022-09-13 | — | — | US | disclosed |
| US-20200129508-A1 | PHARMACEUTICAL COMPOSITION COMPRISING SUBSTANCE INHIBITING ENZYMATIC ACTIVITY OF PEROXIREDOXIN 2 AS EFFECTIVE INGREDIENT FOR TREATMENT OF COLORECTAL CANCER | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2020-04-30 | — | — | US | disclosed |
| US-20200129508-A1 | PHARMACEUTICAL COMPOSITION COMPRISING SUBSTANCE INHIBITING ENZYMATIC ACTIVITY OF PEROXIREDOXIN 2 AS EFFECTIVE INGREDIENT FOR TREATMENT OF COLORECTAL CANCER | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2020-04-30 | — | — | US | disclosed |
| EP-0509717-A2 | New herbicidal compositions | RHONE POULENC AGRICULTURE LTD. (GB) | 1992-10-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200129508-A1 | PHARMACEUTICAL COMPOSITION COMPRISING SUBSTANCE INHIBITING ENZYMATIC ACTIVITY OF PEROXIREDOXIN 2 AS EFFECTIVE INGREDIENT FOR TREATMENT OF COLORECTAL CANCER | TNKS, TNKS2, PRDX2 | SNCA 3420/4885MAPT 3941/4885ALDH1A1 4147/4885 |
| US-11439640-B2 | Pharmaceutical composition comprising substance inhibiting enzymatic activity of peroxiredoxin 2 as effective ingredient for treatment of colorectal cancer | TNKS, TNKS2, PRDX2 | SNCA 3420/4885MAPT 3941/4885ALDH1A1 4147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.