Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5585819 | 0.71 | — | — | |
| SCHEMBL3843628 | 0.71 | — | — | |
| SCHEMBL5586042 | 0.70 | — | — | |
| SCHEMBL5585585 | 0.69 | OPRM1 (0.31) | PARP1 | |
| SCHEMBL5585782 | 0.68 | — | — | |
| SCHEMBL20880455 | 0.67 | — | — | |
| SCHEMBL5585906 | 0.67 | — | — | |
| SCHEMBL9286272 | 0.66 | PARP1 (0.33) | PARP1 | |
| SCHEMBL27793969 | 0.66 | — | — | |
| SCHEMBL5586081 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0275759-B1 | SUBSTITUTED 3-PIPERIDINE AMINES OR 3-AZEPIN AMINES, THEIR PREPARATION AND THERAPEUTIC USES | RIOM LABORATOIRES- C.E.R.M. "R.L.-CERM" - (S.A.) (FR) | 1992-01-29 | — | — | EP | disclosed |