Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11640859 | 0.95 | KDM4E (0.44) | DDB1CRBNNOS3NOS1NOS2 | |
| SCHEMBL8230399 | 0.95 | KDM4E (0.44) | DDB1CRBNNOS3NOS1NOS2 | |
| SCHEMBL11792482 | 0.93 | KDM4E (0.43) | DDB1CRBNGBA1KDM4EALDH1A1 | |
| SCHEMBL11792486 | 0.93 | KDM4E (0.43) | DDB1CRBNGBA1KDM4EALDH1A1 | |
| Ethyl Acetate SCHEMBL9146291 | 0.84 | L3MBTL1 (0.42) | ALDH1A1PTGS1PTGS2OPRK1HTT | |
| SCHEMBL9138675 | 0.83 | PTGS1 (0.43) | ALDH1A1ESR1ESR2PTGS1PTGS2 | |
| SCHEMBL9138676 | 0.83 | PTGS1 (0.43) | ALDH1A1ESR1ESR2PTGS1PTGS2 | |
| Acetic Acid SCHEMBL9146308 | 0.81 | PTGS1 (0.44) | ALDH1A1ESR1ESR2PTGS1PTGS2 | |
| SCHEMBL9584595 | 0.80 | ESR1 (0.43) | KDM4EALDH1A1ESR1ESR2POLB | |
| SCHEMBL9584588 | 0.80 | ESR1 (0.43) | KDM4EALDH1A1ESR1ESR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472449-A2 | Substituted sulfonamides, processes for their preparation and medicines containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1992-02-26 | — | — | EP | disclosed |