Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9674883 | 0.82 | KDM4E (0.52) | KDM4EMAPTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL9672375 | 0.80 | KDM4E (0.50) | KDM4EMAPTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL10567354 | 0.80 | KDM4E (0.56) | KDM4EMAPTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL9674754 | 0.76 | KDM4E (0.62) | KDM4EMAPTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL30995709 | 0.73 | ALDH1A1 (0.57) | KDM4EMAPTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL9262039 | 0.71 | SMN1; SMN2 (0.50) | KDM4EMAPTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL9262044 | 0.71 | SMN1; SMN2 (0.50) | KDM4EMAPTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL9674507 | 0.71 | SMN1; SMN2 (0.50) | KDM4EMAPTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL9673127 | 0.68 | KDM4E (0.41) | KDM4EMAPTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL876883 | 0.68 | MAPT (0.79) | KDM4EMAPTALDH1A1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234045-B1 | A PYRAZOLE OXIME DERIVATIVE AND ITS PRODUCTION AND USE | NIHON NOHYAKU CO., LTD. (JP) | 1992-09-02 | — | — | EP | disclosed |
| EP-0234045-A2 | A pyrazole oxime derivative and its production and use | NIHON NOHYAKU CO., LTD. (JP) | 1987-09-02 | — | — | EP | disclosed |