Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | USP5 | P45974 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1027011 | 0.84 | HPGD (0.68) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL2146965 | 0.84 | MEN1 (0.68) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL477271 | 0.84 | MEN1 (0.58) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL9787788 | 0.82 | HPGD (0.66) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL4233005 | 0.82 | MEN1 (0.66) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| Bromide SCHEMBL10432863 | 0.82 | HPGD (0.66) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL24942737 | 0.81 | MEN1 (0.64) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL630931 | 0.81 | MEN1 (0.64) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL14638103 | 0.81 | MEN1 (0.64) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL250816 | 0.81 | MEN1 (0.64) | MEN1HPGDKMT2AHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276942-B1 | 6-BETA(SUBSTITUTED)-(S)-HYDROXYMETHYLPENICILLANIC ACIDS AND DERIVATIVES THEREOF | PFIZER INC. (US) | 1992-04-01 | — | — | EP | disclosed |
| US-4782050-A | BACTERICIDES | PFIZER INC. (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0276942-A1 | 6-Beta(substituted)-(S)-hydroxymethylpenicillanic acids and derivatives thereof | PFIZER INC. (US) | 1988-08-03 | — | — | EP | disclosed |