Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28800551 | 0.89 | MEN1 (0.49) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| Thiourea SCHEMBL28497498 | 0.89 | MEN1 (0.53) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL9675201 | 0.84 | MEN1 (0.64) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL6094420 | 0.79 | HSD17B10 (0.58) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL1027011 | 0.79 | HPGD (0.68) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL4785512 | 0.79 | MEN1 (0.58) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL7514337 | 0.79 | HSD17B10 (0.58) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL2146965 | 0.79 | MEN1 (0.68) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL9787788 | 0.78 | HPGD (0.66) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL4233005 | 0.78 | MEN1 (0.66) | MEN1HPGDKMT2AHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114656405-A | Preparation method of difluoromethylbenzimidazole | 广州和为医药科技有限公司 | 2022-06-24 | — | — | CN | claimed |
| CN-119371444-A | Difluoromethyl substituted imidazole carbene metal complex and preparation method and application thereof | 中国人民大学 | 2025-01-28 | — | — | CN | disclosed |
| CN-117384140-B | Benzimidazole derivative and application thereof | 沈阳药科大学 | 2024-10-11 | — | — | CN | disclosed |
| CN-115960055-B | N-difluoromethyl benzothiazole/oxazolselenone compound, and preparation method and application thereof | 华南农业大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-115466228-B | N-difluoromethyl triazole selenourea compound with insecticidal, bactericidal and herbicidal functions and application thereof | 华南农业大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-117384140-A | Benzimidazole derivative and application thereof | 沈阳药科大学 | 2024-01-12 | — | — | CN | disclosed |
| CN-114685495-B | N-difluoromethyl diazacyclo selenourea compound with insecticidal, bacteriostatic, herbicidal and anticancer effects and preparation and application thereof | 华南农业大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-115960055-A | N-difluoromethyl benzothiazole/oxazole selenone compound and preparation method and application thereof | 华南农业大学 | 2023-04-14 | — | — | CN | disclosed |
| CN-115466228-A | N-difluoromethyl triazole selenourea compound with insecticidal, bactericidal and weeding functions and application thereof | 华南农业大学 | 2022-12-13 | — | — | CN | disclosed |
| US-20220274968-A1 | Oxazole And Oxadiazole Derivatives Useful As Agonists Of Free Fatty Acid Receptor 1 | GBIOTECH S.À.R.L. (CH) | 2022-09-01 | — | — | US | disclosed |
| US-20090105400-A1 | Imidazolium side chains for example; for example polymers based on 1-methyl-3-(2H,9H,9H-perfluoro-3,6-dioxa-5-methyl-8-nonenyl)-imidazolium trifluoromethanesulfonate; polymer electrolytes for fuel cell, secondary battery, capacitor, dye-sensitized solar cell and electrochromic device | DAIKIN INDUSTRIES, LTD. (JP) | 2009-04-23 | — | — | US | disclosed |
| EP-1983008-A1 | FLUORINE-CONTAINING POLYMER CONTAINING HETEROAROMATIC RING | Daikin Industries, Ltd. (JP) | 2008-10-22 | — | — | EP | disclosed |
| WO-2008032041-A1 | PYRIMIDINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST PI3K ENZYMES | ASTRAZENECA AB (SE) | 2008-03-20 | — | — | WO | disclosed |
| WO-2008032060-A1 | 4-BENZIMIDAZ0LYL-6-M0RPH0LIN0-2-PIPERAZINYLPYRIMIDINE DERIVATIVES AS P13K AND MTOR INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | ASTRAZENECA AB (SE) | 2008-03-20 | — | — | WO | disclosed |
| WO-2008032036-A1 | 6-BENZIMIDAZ0LYL-2-M0RPH0LIN0-4- (AZETIDINE, PYRROLIDINE, PIPERIDINE OR AZEPINE) PYRIMIDINE DERIVATIVES AS PI3K AND MTOR INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | ASTRAZENECA AB (SE) | 2008-03-20 | — | — | WO | disclosed |
| WO-2008032033-A1 | 4-BENZIMIDAZOLYL-2-MORPHOLINO-6-PIPERAZINYLPYRIMIDINE DERIVATIVES AS PI3K AND MTOR INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | ASTRAZENECA AB (SE) | 2008-03-20 | — | — | WO | disclosed |
| WO-2008032089-A1 | 4-BENZIMIDAZ0LYL-2-M0RPH0LIN0-6-PIPERIDIN-4-YLPYRIMIDINE DERIVATIVES AS PI3K AND MTOR INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | ASTRAZENECA AB (SE) | 2008-03-20 | — | — | WO | disclosed |
| EP-1427408-A4 | CYCLIC HYDROXAMIC ACIDS AS INHIBITORS OF MATRIX METALLOPROTEINASES AND/OR TNF-$g(a) CONVERTING ENZYME (TACE) | BRISTOL MYERS SQUIBB CO (US) | 2005-10-26 | — | — | EP | disclosed |
| EP-1427408-A2 | CYCLIC HYDROXAMIC ACIDS AS INHIBITORS OF MATRIX METALLOPROTEINASES AND/OR TNF-$g(a) CONVERTING ENZYME (TACE) | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003024899-A2 | CYCLIC HYDROXAMIC ACIDS AS INHIBITORS OF MATRIX METALLOPROTEINASES AND/OR TNF-α CONVERTING ENZYME (TACE) | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220274968-A1 | Oxazole And Oxadiazole Derivatives Useful As Agonists Of Free Fatty Acid Receptor 1 | FFAR2, FFAR1, FFAR3 | MEN1 4743/4885HPGD 1443/4885KMT2A 3784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.