Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23525080 | 0.84 | POLB (0.35) | POLBL3MBTL1CYP3A4TSHRMAPK1 | |
| SCHEMBL31032207 | 0.81 | POLB (0.37) | POLBL3MBTL1CYP3A4TSHRMAPK1 | |
| SCHEMBL26694479 | 0.80 | POLB (0.33) | POLBL3MBTL1CYP3A4TSHRMAPK1 | |
| SCHEMBL26694576 | 0.80 | POLB (0.33) | POLBL3MBTL1CYP3A4TSHRMAPK1 | |
| SCHEMBL10529865 | 0.77 | POLB (0.36) | POLBL3MBTL1ALDH1A1 | |
| SCHEMBL30898001 | 0.77 | SOS1 (0.36) | POLBL3MBTL1 | |
| SCHEMBL30699773 | 0.76 | ALDH1A1 (0.38) | POLBL3MBTL1CYP3A4TSHRMAPK1 | |
| SCHEMBL1494426 | 0.76 | ALDH1A1 (0.38) | POLBL3MBTL1CYP3A4TSHRMAPK1 | |
| SCHEMBL27051857 | 0.76 | PRKDC (0.32) | POLBL3MBTL1 | |
| SCHEMBL2353610 | 0.75 | ALDH1A1 (0.33) | CYP3A4TSHRMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237955-B1 | QUINOLONECARBOXYLIC ACID DERIVATIVES AND THEIR PREPARATION | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1992-07-15 | — | — | EP | disclosed |
| US-4894458-A | BACTERICIDES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1990-01-16 | — | — | US | disclosed |
| EP-0237955-A2 | Quinolonecarboxylic acid derivatives and their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-09-23 | — | — | EP | disclosed |