Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9674389 | 0.89 | ADRA1A (0.60) | ADRA1APDE4DALDH1A1TDP1NPSR1 | |
| SCHEMBL9706769 | 0.89 | ADRA1A (0.60) | ADRA1APDE4DALDH1A1TDP1NPSR1 | |
| SCHEMBL9672872 | 0.88 | ADRA1A (0.59) | ADRA1APDE4DALDH1A1NPSR1NPC1 | |
| SCHEMBL9674557 | 0.88 | ADRA1A (0.59) | ADRA1APDE4DALDH1A1NPC1RAB9A | |
| SCHEMBL9672860 | 0.88 | ADRA1A (0.62) | ADRA1APDE4DALDH1A1TDP1NPSR1 | |
| SCHEMBL9675950 | 0.87 | ADRA1A (0.57) | ADRA1APDE4DALDH1A1NPC1RAB9A | |
| SCHEMBL9672809 | 0.85 | ADRA1A (0.59) | ADRA1APDE4DALDH1A1TDP1KDM4E | |
| SCHEMBL9706762 | 0.85 | ADRA1A (0.55) | ADRA1APDE4DALDH1A1TDP1NPSR1 | |
| SCHEMBL9672771 | 0.85 | ADRA1A (0.55) | ADRA1APDE4DNPC1RAB9AMAPT | |
| SCHEMBL9673951 | 0.81 | ADRA1A (0.50) | ADRA1APDE4DALDH1A1TDP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158950-A | Treatment of liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-10-27 | — | — | US | disclosed |
| EP-0298040-B1 | 1,3-DITHIOL-2-YLIDENE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1992-08-26 | — | — | EP | disclosed |