Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309353 | 0.91 | AGTR1 (0.52) | AGTR1 | |
| SCHEMBL9859843 | 0.91 | AGTR1 (0.58) | AGTR1 | |
| SCHEMBL9311385 | 0.89 | AGTR1 (0.52) | AGTR1 | |
| SCHEMBL9309190 | 0.87 | — | — | |
| SCHEMBL7300264 | 0.85 | AGTR1 (0.48) | AGTR1 | |
| SCHEMBL9309869 | 0.84 | — | — | |
| SCHEMBL9310583 | 0.84 | — | — | |
| SCHEMBL9308205 | 0.83 | AGTR1 (0.59) | AGTR1 | |
| SCHEMBL7309005 | 0.83 | AGTR1 (0.49) | AGTR1 | |
| SCHEMBL9309893 | 0.82 | AGTR1 (0.48) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992020673-A1 | ANTIHYPOTENSIVE BENZOFURAN DERIVATIVES WITH N-LINKED 1H-IMIDAZOLYLMETHYL-5-CARBOXAMIDE SUBSTITUENTS | GLAXO GROUP LIMITED (GB) | 1992-11-26 | — | — | WO | disclosed |
| EP-0514216-A1 | Antihypotensive benzofuran derivatives with N-linked 1H-imidazolyl-methyl-5-carboxamide substituents | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |