Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.38 |
| ▸ | AHCY | P23526 | 4/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9674847 | 0.89 | FAP (0.38) | CYP3A4FGFR1AHCYADORA2AADORA1 | |
| SCHEMBL9675613 | 0.87 | CYP3A4 (0.44) | CYP3A4FGFR1AHCYADORA2AADORA1 | |
| SCHEMBL9684215 | 0.83 | ADORA2A (0.40) | CYP3A4FGFR1AHCYADORA2AADORA1 | |
| SCHEMBL9555527 | 0.81 | FAP (0.44) | CYP3A4FGFR1AHCYADORA2AADORA1 | |
| SCHEMBL9555568 | 0.81 | FAP (0.44) | CYP3A4FGFR1AHCYADORA2AADORA1 | |
| SCHEMBL9417158 | 0.81 | FAP (0.44) | CYP3A4FGFR1AHCYADORA2AADORA1 | |
| SCHEMBL9677354 | 0.81 | PNP (0.44) | CYP3A4 | |
| SCHEMBL9675797 | 0.81 | HSP90AA1 (0.33) | — | |
| SCHEMBL9675785 | 0.81 | HSP90AA1 (0.33) | — | |
| SCHEMBL9858011 | 0.80 | SLC22A6 (0.43) | CYP3A4FGFR1AHCYADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399743-A1 | Phosphonomethylthio-alkoseypureine derivatives, intermediate products for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1990-11-28 | — | — | EP | claimed |
| US-5108994-A | Synergistic with interferon; herpes virus | BEECHAM GROUP P.L.C. (GB) | 1992-04-28 | — | — | US | disclosed |
| EP-0399743-A1 | Phosphonomethylthio-alkoseypureine derivatives, intermediate products for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1990-11-28 | — | — | EP | disclosed |