Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30237358 | 0.86 | TSHR (0.47) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL9676449 | 0.85 | TDP1 (0.50) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL19501351 | 0.80 | TSHR (0.48) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL1505782 | 0.79 | TDP1 (0.45) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL27768818 | 0.78 | TSHR (0.47) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL21373613 | 0.78 | TSHR (0.52) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL28102481 | 0.78 | ALDH1A1 (0.44) | TSHRCYP3A4ALDH1A1TDP1MEN1 | |
| SCHEMBL31543948 | 0.78 | CYP1A2 (0.47) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL30857795 | 0.76 | TSHR (0.53) | TSHRCYP3A4ALDH1A1RECQLTDP1 | |
| SCHEMBL1635417 | 0.76 | TSHR (0.53) | TSHRCYP3A4ALDH1A1RECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237955-B1 | QUINOLONECARBOXYLIC ACID DERIVATIVES AND THEIR PREPARATION | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1992-07-15 | — | — | EP | disclosed |
| US-4894458-A | BACTERICIDES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1990-01-16 | — | — | US | disclosed |
| EP-0237955-A2 | Quinolonecarboxylic acid derivatives and their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-09-23 | — | — | EP | disclosed |