Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2771123 | 1.00 | DUT (0.36) | DUTAPPS1PR1EPHX2 | |
| SCHEMBL10978347 | 0.98 | DUT (0.37) | DUTAPPS1PR1 | |
| SCHEMBL1743321 | 0.95 | DUT (0.34) | DUTAPPS1PR1 | |
| SCHEMBL10984457 | 0.93 | DUT (0.38) | DUTAPP | |
| SCHEMBL18095405 | 0.83 | DUT (0.38) | DUTAPP | |
| SCHEMBL16426513 | 0.83 | DUT (0.38) | DUTAPP | |
| SCHEMBL14245094 | 0.80 | DUT (0.42) | DUT | |
| SCHEMBL27241092 | 0.80 | DUT (0.42) | DUT | |
| SCHEMBL9007756 | 0.80 | DUT (0.42) | DUT | |
| SCHEMBL8063404 | 0.78 | DUT (0.43) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232912-B1 | HYDROXAMIC ACIDS OF 7-OXABICYCLOHEPTANE SUBSTITUTED ETHERS | E.R. Squibb & Sons, Inc. (US) | 1992-05-13 | — | — | EP | disclosed |
| EP-0232912-A1 | Hydroxamic acids of 7-oxabicycloheptane substituted ethers | E.R. Squibb & Sons, Inc. (US) | 1987-08-19 | — | — | EP | disclosed |
| US-4654366-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPSORIATIC | E. R. SQUIBB & SONS, INC. (US) | 1987-03-31 | — | — | US | disclosed |
| EP-0163562-A1 | 7-Oxabicycloheptane substituted ethers | E.R. Squibb & Sons, Inc. (US) | 1985-12-04 | — | — | EP | disclosed |
| US-4550120-A | BRONCHODILATOR AGENTS, ANALGESICS | E. R. SQUIBB & SONS, INC. (US) | 1985-10-29 | — | — | US | disclosed |
| EP-0140307-A2 | 7-Oxabicycloheptane ethers | E.R. Squibb & Sons, Inc. (US) | 1985-05-08 | — | — | EP | disclosed |
| US-4513103-A | 7-Oxabicycloheptane ethers useful in the treatment of thrombolytic disease | E. R. SQUIBB & SONS, INC. (US) | 1985-04-23 | — | — | US | disclosed |