SCHEMBL967571

SCHEMBL967571

C=C(C)C(=O)OCc1ccccc1.C=CCOC(=O)C(=C)CC=C(C)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
CYP3A4 P08684 1/20 0.36
HCAR2 Q8TDS4 1/20 0.35
MAPK1 P28482 2/20 0.34
KMT2A Q03164 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A3 Q01959 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
LMNA P02545 2/20 0.33
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
FAAH O00519 1/20 0.33
TGM2 P21980 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
ALOX15 P16050 1/20 0.33
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7161135 1.00 ALDH1A1 (0.40) ALDH1A1CYP3A4HCAR2MAPK1KMT2A
SCHEMBL4580895 0.94 ALDH1A1 (0.36) ALDH1A1CYP3A4HCAR2MAPK1KMT2A
SCHEMBL189711 0.89 ALDH1A1 (0.50) ALDH1A1HCAR2MAPK1KMT2AL3MBTL1
SCHEMBL1228085 0.87 ALDH1A1 (0.43) ALDH1A1HCAR2MAPK1KMT2AL3MBTL1
SCHEMBL2097594 0.87 ALDH1A1 (0.43) ALDH1A1HCAR2MAPK1KMT2AL3MBTL1
Acrylic Acid SCHEMBL3104873 0.87 ALDH1A1 (0.45) ALDH1A1HCAR2MAPK1KMT2AL3MBTL1
Methacrylic Acid SCHEMBL3455649 0.87 ALDH1A1 (0.50) ALDH1A1CYP3A4HCAR2MAPK1KMT2A
SCHEMBL22419031 0.87 ALDH1A1 (0.53) ALDH1A1CYP3A4HCAR2MAPK1KMT2A
SCHEMBL1855787 0.86 ALDH1A1 (0.40) ALDH1A1CYP3A4HCAR2MAPK1KMT2A
SCHEMBL195082 0.86 ALDH1A1 (0.40) ALDH1A1CYP3A4HCAR2MAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102227685-A Gumming compositions with nano-particles for improving scratch sensitivity in image and non-image areas of lithographic printing plates EASTMAN KODAK CO 2011-10-26 CN disclosed
US-20110223540-A1 GUMMING COMPOSITIONS WITH NANO-PARTICLES FOR IMPROVING SCRATCH SENSITIVITY IN IMAGE AND NON-IMAGE AREAS OF LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK COMPANY 2011-09-15 US disclosed
US-20110003123-A1 SENSITIZER/INITIATOR COMBINATION FOR NEGATIVE-WORKING THERMAL-SENSITIVE COMPOSITIONS USABLE FOR LITHOGRAPHIC PLATES KODAK GRAPHIC COMMUNICATIONS, GMBH (DE) 2011-01-06 US disclosed
WO-2010063763-A1 GUMMING COMPOSITIONS WITH NANO-PARTICLES FOR IMPROVING SCRATCH SENSITIVITY IN IMAGE AND NON-IMAGE AREAS OF LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK COMPANY (US) 2010-06-10 WO disclosed
EP-2194429-A1 Gumming compositions with nano-particles for improving scratch sensitivity in image and non-image areas of lithographic printing plates EASTMAN KODAK COMPANY (US) 2010-06-09 EP disclosed
WO-2009109579-A1 SENSITIZER/INITIATOR COMBINATION FOR NEGATIVE-WORKING THERMAL-SENSITIVE COMPOSITIONS USABLE FOR LITHOGRAPHIC PLATES EASTMAN KODAK COMPANY (US) 2009-09-11 WO disclosed
EP-2098367-A1 Sensitizer/Initiator Combination for Negative-Working Thermal-Sensitive Compositions Usable for Lithographic Plates EASTMAN KODAK COMPANY (US) 2009-09-09 EP disclosed