Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10621265 | 0.89 | CYP3A4 (0.47) | CYP3A4L3MBTL1CA2TSHRATM | |
| SCHEMBL6018584 | 0.86 | CYP3A4 (0.37) | CYP3A4L3MBTL1CA12CA1CA2 | |
| SCHEMBL5520912 | 0.85 | TSHR (0.33) | TSHR | |
| SCHEMBL6018680 | 0.80 | CYP3A4 (0.49) | CYP3A4L3MBTL1CA2TSHRATM | |
| SCHEMBL3763866 | 0.73 | TSHR (0.38) | CYP3A4TSHRTDP1 | |
| SCHEMBL12059295 | 0.72 | CA12 (0.32) | CA12CA1CA2CA7CA14 | |
| SCHEMBL7389655 | 0.70 | TSHR (0.31) | CYP3A4L3MBTL1TSHR | |
| SCHEMBL4655215 | 0.70 | TSHR (0.39) | CA12CA1CA2CA7CA14 | |
| SCHEMBL6018309 | 0.70 | MAPT (0.31) | — | |
| SCHEMBL2219107 | 0.69 | TSHR (0.35) | CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483633-A1 | 8-Azabicyclo[3.2.1]octylalkylthiazolidinones, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-05-06 | — | — | EP | disclosed |