Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9675810 | 0.89 | MAPT (0.45) | IDO1F10AMY1AMAOAMAOB | |
| SCHEMBL9673902 | 0.80 | MAPT (0.63) | SMN1; SMN2MAPTLMNATSHR | |
| SCHEMBL38662484 | 0.78 | HSD17B10 (0.67) | IDO1F10MAOAMAOBMPO | |
| SCHEMBL38661086 | 0.77 | IDO1 (0.59) | IDO1F10AMY1AMAOAMAOB | |
| SCHEMBL10271748 | 0.76 | IDO1 (0.66) | IDO1F10AMY1AMPOALPL | |
| SCHEMBL31345724 | 0.76 | IDO1 (0.66) | IDO1F10AMY1AMPOALPL | |
| SCHEMBL6640558 | 0.76 | IDO1 (0.66) | IDO1F10AMY1AMPOALPL | |
| SCHEMBL5796915 | 0.75 | IDO1 (0.50) | IDO1F10AMY1AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL5810121 | 0.74 | IDO1 (0.49) | IDO1F10MAOAMAOBMPO | |
| SCHEMBL8071539 | 0.73 | HRH4 (0.60) | IDO1AMY1AMPOALPLALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276942-B1 | 6-BETA(SUBSTITUTED)-(S)-HYDROXYMETHYLPENICILLANIC ACIDS AND DERIVATIVES THEREOF | PFIZER INC. (US) | 1992-04-01 | — | — | EP | disclosed |
| US-4782050-A | BACTERICIDES | PFIZER INC. (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0276942-A1 | 6-Beta(substituted)-(S)-hydroxymethylpenicillanic acids and derivatives thereof | PFIZER INC. (US) | 1988-08-03 | — | — | EP | disclosed |