Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9675828 | 0.89 | IDO1 (0.54) | MAPTSMN1; SMN2MAPK1MEN1LMNA | |
| SCHEMBL9673902 | 0.80 | MAPT (0.63) | MAPTSMN1; SMN2LMNAHSD17B10ALDH1A1 | |
| SCHEMBL9513404 | 0.77 | TSHR (0.47) | MAPTSMN1; SMN2LMNAHSD17B10ALDH1A1 | |
| SCHEMBL9847737 | 0.76 | HSD17B10 (0.54) | MAPTSMN1; SMN2LMNAHSD17B10ALDH1A1 | |
| SCHEMBL8417202 | 0.76 | DDAH1 (0.58) | MAPTMEN1LMNAKMT2AHSD17B10 | |
| SCHEMBL5774011 | 0.76 | TDP1 (0.51) | LMNAHSD17B10ALDH1A1KDM4EIDO1 | |
| SCHEMBL13351516 | 0.73 | IDO1 (0.54) | KMT2AALDH1A1KDM4EIDO1 | |
| SCHEMBL8071535 | 0.73 | HRH4 (0.47) | MAPTLMNAHSD17B10ALDH1A1KDM4E | |
| SCHEMBL20867740 | 0.72 | IDO1 (0.57) | ALDH1A1KDM4EIDO1F10 | |
| SCHEMBL1083641 | 0.72 | IDO1 (0.49) | ALDH1A1KDM4EIDO1RAB9AF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276942-B1 | 6-BETA(SUBSTITUTED)-(S)-HYDROXYMETHYLPENICILLANIC ACIDS AND DERIVATIVES THEREOF | PFIZER INC. (US) | 1992-04-01 | — | — | EP | disclosed |
| US-4782050-A | BACTERICIDES | PFIZER INC. (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0276942-A1 | 6-Beta(substituted)-(S)-hydroxymethylpenicillanic acids and derivatives thereof | PFIZER INC. (US) | 1988-08-03 | — | — | EP | disclosed |