Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 15/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | VCP | P55072 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | PNP | P00491 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10448323 | 1.00 | HPRT1 (0.52) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL10448313 | 1.00 | HPRT1 (0.52) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9677354 | 0.88 | PNP (0.44) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9684414 | 0.83 | HPRT1 (0.56) | HPRT1PNP | |
| SCHEMBL9555507 | 0.81 | HPRT1 (0.58) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9417201 | 0.81 | HPRT1 (0.58) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9555352 | 0.81 | HPRT1 (0.58) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL8834028 | 0.81 | BLM (0.57) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9685349 | 0.80 | HPRT1 (0.59) | HPRT1PNP | |
| SCHEMBL9185750 | 0.80 | BLM (0.56) | HPRT1MEN1ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399743-A1 | Phosphonomethylthio-alkoseypureine derivatives, intermediate products for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1990-11-28 | — | — | EP | claimed |
| US-5108994-A | Synergistic with interferon; herpes virus | BEECHAM GROUP P.L.C. (GB) | 1992-04-28 | — | — | US | disclosed |
| EP-0399743-A1 | Phosphonomethylthio-alkoseypureine derivatives, intermediate products for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1990-11-28 | — | — | EP | disclosed |