Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ATP4A | P20648 | 1/20 | 0.39 |
| ▸ | ATP4B | P51164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CHRNE | Q04844 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6482665 | 0.85 | ATP4A (0.39) | MAPTATP4AATP4BHTTLMNA | |
| SCHEMBL9396516 | 0.84 | ATP4A (0.40) | MAPTMEN1KMT2AATP4AATP4B | |
| SCHEMBL9395786 | 0.83 | ATP4A (0.39) | MAPTMEN1KMT2AATP4AATP4B | |
| SCHEMBL9395890 | 0.83 | ATP4A (0.39) | MAPTMEN1KMT2AATP4AATP4B | |
| SCHEMBL3689535 | 0.82 | ATP4A (0.52) | MEN1KMT2AATP4AATP4BALDH1A1 | |
| SCHEMBL30637598 | 0.82 | ATP4A (0.52) | MEN1KMT2AATP4AATP4BALDH1A1 | |
| SCHEMBL10333180 | 0.82 | MAPT (0.42) | MAPTMEN1KMT2AALDH1A1RIPK1 | |
| SCHEMBL10703138 | 0.81 | ATP4A (0.37) | MAPTATP4AATP4BHTTLMNA | |
| SCHEMBL9678832 | 0.81 | ATP4A (0.39) | MAPTMEN1KMT2AATP4AATP4B | |
| SCHEMBL6475466 | 0.81 | ATP4A (0.39) | MAPTMEN1KMT2AATP4AATP4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174717-B1 | BENZIMIDAZOLES, AND THEIR PRODUCTION FORMULATION AND USE AS GASTRIC ACID SECRETION INHIBITORS | FISONS plc (GB) | 1992-01-22 | — | — | EP | claimed |
| CN-85106252-A | The preparation method of compound and application thereof | — | 1986-06-10 | — | — | CN | claimed |
| EP-0174717-A1 | Benzimidazoles, and their production formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1986-03-19 | — | — | EP | claimed |
| EP-0174717-B1 | BENZIMIDAZOLES, AND THEIR PRODUCTION FORMULATION AND USE AS GASTRIC ACID SECRETION INHIBITORS | FISONS plc (GB) | 1992-01-22 | — | — | EP | disclosed |
| CN-85106252-A | The preparation method of compound and application thereof | — | 1986-06-10 | — | — | CN | disclosed |
| EP-0174717-A1 | Benzimidazoles, and their production formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1986-03-19 | — | — | EP | disclosed |