Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 2/20 | 0.41 |
| ▸ | ATP4B | P51164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CFB | P00751 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9677072 | 0.88 | ATP4A (0.46) | ATP4AATP4BALDH1A1NPC1RAB9A | |
| SCHEMBL9395841 | 0.84 | ATP4A (0.40) | ATP4AATP4BALDH1A1NPC1RAB9A | |
| SCHEMBL6475152 | 0.84 | ATP4A (0.56) | ATP4AATP4BALDH1A1NPC1RAB9A | |
| Water SCHEMBL6483945 | 0.83 | ATP4A (0.55) | ATP4AATP4BALDH1A1NPC1RAB9A | |
| Water SCHEMBL6483950 | 0.83 | ATP4A (0.55) | ATP4AATP4BALDH1A1NPC1RAB9A | |
| SCHEMBL3689535 | 0.78 | ATP4A (0.52) | ATP4AATP4BALDH1A1NPC1RAB9A | |
| SCHEMBL30637598 | 0.78 | ATP4A (0.52) | ATP4AATP4BALDH1A1NPC1RAB9A | |
| SCHEMBL9398067 | 0.78 | ATP4A (0.42) | ATP4AATP4BALDH1A1NPC1RAB9A | |
| SCHEMBL10726467 | 0.77 | ATP4A (0.51) | ATP4AATP4BALDH1A1NPC1RAB9A | |
| SCHEMBL9675855 | 0.75 | ATP4A (0.41) | ATP4AATP4BALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174717-B1 | BENZIMIDAZOLES, AND THEIR PRODUCTION FORMULATION AND USE AS GASTRIC ACID SECRETION INHIBITORS | FISONS plc (GB) | 1992-01-22 | — | — | EP | claimed |
| EP-0174717-A1 | Benzimidazoles, and their production formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1986-03-19 | — | — | EP | claimed |
| EP-0174717-A1 | Benzimidazoles, and their production formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1986-03-19 | — | — | EP | disclosed |