Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 17/20 | 0.60 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9677816 | 0.95 | SIGMAR1 (0.67) | SIGMAR1OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL9676995 | 0.95 | SIGMAR1 (0.64) | SIGMAR1OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL9676109 | 0.94 | SIGMAR1 (0.56) | SIGMAR1OPRL1OPRM1OPRK1 | |
| SCHEMBL9678352 | 0.92 | SIGMAR1 (0.65) | SIGMAR1 | |
| SCHEMBL9676251 | 0.92 | SIGMAR1 (0.65) | SIGMAR1OPRL1OPRM1OPRK1 | |
| SCHEMBL9677190 | 0.92 | SIGMAR1 (0.68) | SIGMAR1OPRL1OPRM1OPRK1 | |
| SCHEMBL9679004 | 0.91 | SIGMAR1 (0.64) | SIGMAR1OPRL1OPRM1OPRK1 | |
| SCHEMBL9678835 | 0.91 | SIGMAR1 (0.67) | SIGMAR1OPRL1OPRM1OPRK1 | |
| SCHEMBL9844330 | 0.91 | OPRL1 (0.54) | SIGMAR1OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL9677766 | 0.89 | SIGMAR1 (0.69) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300272-B1 | OXAZOLIDINONES | MERCK PATENT GmbH (DE) | 1992-09-16 | — | — | EP | disclosed |
| US-4970217-A | NEUROLEPTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-11-13 | — | — | US | disclosed |
| EP-0300272-A1 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1989-01-25 | — | — | EP | disclosed |