Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678495 | 0.85 | KDM4E (0.45) | KDM4EPOLBGAACYP1A2ALDH1A1 | |
| SCHEMBL9677625 | 0.84 | KDM4E (0.44) | KDM4EPOLBGAACYP1A2ALDH1A1 | |
| SCHEMBL10567999 | 0.79 | KDM4E (0.48) | KDM4EPOLBCYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9679660 | 0.75 | ALDH1A1 (0.48) | KDM4EPOLBGAACYP1A2ALDH1A1 | |
| SCHEMBL9677379 | 0.73 | SMN1; SMN2 (0.44) | KDM4EPOLBCYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9677293 | 0.73 | ALDH1A1 (0.49) | KDM4ECYP1A2ALDH1A1MAPTHPGD | |
| SCHEMBL9679484 | 0.71 | KDM4E (0.46) | KDM4EGAACYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9679620 | 0.71 | CYP1A2 (0.43) | KDM4EPOLBGAACYP1A2ALDH1A1 | |
| SCHEMBL9664890 | 0.71 | PIK3CG (0.34) | KDM4EALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL9679665 | 0.70 | CYP1A2 (0.42) | KDM4EPOLBGAACYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150507-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR PRODUCING THE SAME AND COMPOSITIONS CONTAINING THEM | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-05 | — | — | EP | disclosed |
| US-5064953-A | INTERMEDIATES CEPHALOSPORIN DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1991-11-12 | — | — | US | disclosed |
| US-4888332-A | ANTIBIOTICS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1989-12-19 | — | — | US | disclosed |
| EP-0150507-A2 | Cephalosporin derivatives, processes for producing the same and compositions containing them | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1985-08-07 | — | — | EP | disclosed |