Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.83 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | PPOX | P50336 | 1/20 | 0.48 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | PNLIP | P16233 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bifenox SCHEMBL8541647 | 0.91 | TDP1 (1.00) | TDP1MEN1KMT2ATTRPPOX | |
| Bifenox SCHEMBL38816 | 0.91 | TDP1 (1.00) | TDP1MEN1KMT2ATTRPPOX | |
| Bifenox SCHEMBL30862569 | 0.91 | TDP1 (1.00) | TDP1MEN1KMT2ATTRPPOX | |
| Bifenox SCHEMBL28419037 | 0.89 | TDP1 (0.98) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL27272224 | 0.86 | TDP1 (0.61) | TDP1MEN1KMT2ATTRPPOX | |
| Bifenox SCHEMBL27552005 | 0.85 | TDP1 (0.89) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11408337 | 0.83 | TDP1 (0.71) | TDP1TTRALDH1A1NPSR1MAPT | |
| SCHEMBL1315721 | 0.83 | TDP1 (0.59) | TDP1HPGDALDH1A1MAPTPOLB | |
| SCHEMBL1679893 | 0.83 | TDP1 (0.71) | TDP1MEN1KMT2ATTRPPOX | |
| Bifenox SCHEMBL9427373 | 0.83 | TDP1 (0.84) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| EP-0270138-B1 | SUBSTITUTED 2-PHENYLIMINO-OXAZOLIDINE COMPOUNDS HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1991-05-29 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| US-4854961-A | Substituted 2-phenylimino-oxazolidine compounds having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1989-08-08 | — | — | US | disclosed |
| EP-0270138-A1 | Substituted 2-phenylimino-oxazolidine compounds having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-08 | — | — | EP | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |