Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | CCR2 | P41597 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9677965 | 0.84 | MAOA (0.37) | KDM1ASLC6A4SLC6A3SLC6A2OPRM1 | |
| SCHEMBL8950585 | 0.76 | KDM1A (0.47) | KCNN4KDM1ACCR2SLC6A4SLC6A3 | |
| SCHEMBL9676485 | 0.75 | SLC6A4 (0.34) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL9677345 | 0.72 | SLC6A2 (0.30) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL9678052 | 0.71 | — | — | |
| SCHEMBL9678092 | 0.70 | — | — | |
| SCHEMBL8950566 | 0.67 | KDM1A (0.45) | KCNN4KDM1ACCR2SLC6A4SLC6A3 | |
| SCHEMBL10193786 | 0.66 | KDM1A (0.54) | KCNN4KDM1ACCR2SLC6A4SLC6A3 | |
| SCHEMBL10468722 | 0.65 | KDM1A (0.54) | KCNN4KDM1ACCR2SLC6A4SLC6A3 | |
| SCHEMBL5698913 | 0.64 | KDM1A (0.51) | KCNN4KDM1ACCR2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0294229-B1 | NOVEL HETEROCYCLIC PESTICIDAL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-12-02 | — | — | EP | claimed |
| EP-0294229-B1 | NOVEL HETEROCYCLIC PESTICIDAL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-12-02 | — | — | EP | disclosed |