Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.59 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.46 |
| ▸ | SMG1 | Q96Q15 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 3/20 | 0.44 |
| ▸ | FLT3 | P36888 | 3/20 | 0.44 |
| ▸ | NR2C2 | P49116 | 1/20 | 0.44 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3811303 | 0.84 | OGA (0.59) | OGAHRH4PIK3CAPIK3CDMEN1 | |
| SCHEMBL22903930 | 0.80 | OGA (0.55) | OGAHRH4PIK3CAPIK3CDMEN1 | |
| SCHEMBL28085067 | 0.79 | PLK4 (0.68) | JAK2FLT3PLK4 | |
| SCHEMBL1089586 | 0.79 | CXCR4 (0.74) | OGAHRH4PIK3CAPIK3CDCXCR4 | |
| SCHEMBL12963702 | 0.79 | OGA (0.68) | OGAHRH4PIK3CAPIK3CDCXCR4 | |
| SCHEMBL28118781 | 0.79 | SMG1 (0.70) | OGAALDH1A1SMG1JAK2FLT3 | |
| SCHEMBL29790016 | 0.78 | PIK3CA (0.50) | OGAPIK3CAPIK3CDMEN1USP2 | |
| SCHEMBL21914804 | 0.78 | PIK3CA (0.50) | OGAPIK3CAPIK3CDMEN1USP2 | |
| SCHEMBL23174113 | 0.77 | HRH4 (0.70) | OGAHRH4CXCR4MKNK1MKNK2 | |
| SCHEMBL12933414 | 0.77 | HRH4 (0.74) | OGAHRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098902-A | Administering 5-bromo-4- 4-morpholinyl!-2-pyridinamine or 4- 4-morpholinyl-2- 1-piperazinyl!thieno 3,2-d!pyrimidine for cognitive activators | WARNER-LAMBERT COMPANY (US) | 1992-03-24 | — | — | US | claimed |