Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678606 | 0.94 | SIGMAR1 (0.83) | SIGMAR1 | |
| SCHEMBL9679057 | 0.92 | SIGMAR1 (0.82) | SIGMAR1 | |
| SCHEMBL9844117 | 0.91 | SIGMAR1 (0.68) | SIGMAR1 | |
| SCHEMBL9677898 | 0.91 | SIGMAR1 (0.81) | SIGMAR1 | |
| SCHEMBL9676413 | 0.90 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL9676885 | 0.90 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL9679038 | 0.89 | SIGMAR1 (0.69) | SIGMAR1 | |
| SCHEMBL9676443 | 0.87 | SIGMAR1 (0.80) | SIGMAR1 | |
| SCHEMBL9678654 | 0.87 | SIGMAR1 (0.78) | SIGMAR1 | |
| SCHEMBL9677788 | 0.86 | SIGMAR1 (0.77) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300272-B1 | OXAZOLIDINONES | MERCK PATENT GmbH (DE) | 1992-09-16 | — | — | EP | disclosed |
| US-4970217-A | NEUROLEPTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-11-13 | — | — | US | disclosed |
| EP-0300272-A1 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1989-01-25 | — | — | EP | disclosed |