Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.63 |
| ▸ | MEN1 | O00255 | 7/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.54 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678777 | 0.94 | TDP1 (0.57) | KMT2AMEN1SMN1; SMN2TDP1SOAT2 | |
| SCHEMBL9678931 | 0.94 | KMT2A (0.57) | KMT2AMEN1SMN1; SMN2TDP1SOAT2 | |
| SCHEMBL9678946 | 0.92 | KMT2A (0.56) | KMT2AMEN1SMN1; SMN2TDP1SOAT2 | |
| SCHEMBL9680214 | 0.92 | KMT2A (0.56) | KMT2AMEN1SMN1; SMN2TDP1SOAT2 | |
| SCHEMBL9680654 | 0.92 | KMT2A (0.56) | KMT2AMEN1SMN1; SMN2TDP1SOAT2 | |
| SCHEMBL9678843 | 0.91 | TDP1 (0.58) | KMT2AMEN1SMN1; SMN2TDP1SOAT2 | |
| SCHEMBL9681131 | 0.91 | KMT2A (0.57) | KMT2AMEN1SMN1; SMN2TDP1SOAT2 | |
| SCHEMBL9680195 | 0.90 | KMT2A (0.54) | KMT2AMEN1SMN1; SMN2TDP1SOAT2 | |
| SCHEMBL9680212 | 0.90 | KMT2A (0.54) | KMT2AMEN1SMN1; SMN2TDP1SOAT2 | |
| SCHEMBL9680704 | 0.90 | KMT2A (0.72) | KMT2AMEN1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | claimed |
| JP-3148247-A | — | — | None | — | — | JP | disclosed |
| US-5153226-A | Administering as anticholesterol agents, for atherosclerosis | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| JP-H03148247-A | ACAT INHIBITOR | WARNER LAMBERT CO | 1991-06-25 | — | — | JP | disclosed |
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |