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SCHEMBL9680195

SCHEMBL9680195

CC(C)c1cccc(C(C)C)c1NC(=O)CNC(c1ccccc1)c1ccc2ccccc2c1

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 9/20 0.54
▸ MEN1 O00255 7/20 0.54
▸ TDP1 Q9NUW8 1/20 0.51
▸ SMN1; SMN2 Q16637 1/20 0.48
▸ KDM4E B2RXH2 1/20 0.47
▸ SOAT2 O75908 1/20 0.46
▸ SOAT1 P35610 1/20 0.46
▸ LMNA P02545 2/20 0.45
▸ ALDH1A1 P00352 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9679362 0.90 KMT2A (0.63) KMT2AMEN1TDP1SMN1; SMN2KDM4E
SCHEMBL9678843 0.87 TDP1 (0.58) KMT2AMEN1TDP1SMN1; SMN2KDM4E
SCHEMBL9678777 0.87 TDP1 (0.57) KMT2AMEN1TDP1SMN1; SMN2KDM4E
SCHEMBL9678931 0.87 KMT2A (0.57) KMT2AMEN1TDP1SMN1; SMN2KDM4E
SCHEMBL9680212 0.86 KMT2A (0.54) KMT2AMEN1TDP1SMN1; SMN2KDM4E
SCHEMBL9680704 0.86 KMT2A (0.72) KMT2AMEN1TDP1SMN1; SMN2
SCHEMBL9680654 0.86 KMT2A (0.56) KMT2AMEN1TDP1SMN1; SMN2KDM4E
SCHEMBL9680214 0.86 KMT2A (0.56) KMT2AMEN1TDP1SMN1; SMN2KDM4E
SCHEMBL9678946 0.86 KMT2A (0.56) KMT2AMEN1TDP1SMN1; SMN2KDM4E
SCHEMBL9678786 0.85 KMT2A (0.53) KMT2AMEN1TDP1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5153226-A Administering as anticholesterol agents, for atherosclerosis WARNER-LAMBERT COMPANY (US) 1992-10-06 — — US disclosed