Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.77 |
| ▸ | MEN1 | O00255 | 3/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.53 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843989 | 0.83 | KMT2A (0.58) | KMT2AMEN1SMN1; SMN2SOAT2SOAT1 | |
| SCHEMBL9678591 | 0.82 | KMT2A (0.63) | KMT2AMEN1KDM4ESMN1; SMN2SOAT2 | |
| SCHEMBL9678933 | 0.82 | KMT2A (0.63) | KMT2AMEN1KDM4ESMN1; SMN2SOAT2 | |
| SCHEMBL9678585 | 0.82 | KMT2A (0.63) | KMT2AMEN1KDM4ESMN1; SMN2SOAT2 | |
| SCHEMBL9463084 | 0.82 | KMT2A (0.67) | KMT2AMEN1KDM4ESMN1; SMN2SOAT2 | |
| SCHEMBL9679362 | 0.82 | KMT2A (0.63) | KMT2AMEN1KDM4ESMN1; SMN2SOAT2 | |
| SCHEMBL8321568 | 0.80 | — | — | |
| SCHEMBL9316603 | 0.79 | SOAT1 (0.58) | KMT2AMEN1KDM4ESMN1; SMN2SOAT2 | |
| SCHEMBL9679244 | 0.78 | KMT2A (0.52) | KMT2AMEN1LMNA | |
| SCHEMBL9317463 | 0.77 | SOAT1 (0.67) | KMT2AMEN1KDM4ESMN1; SMN2SOAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | claimed |
| US-5153226-A | Administering as anticholesterol agents, for atherosclerosis | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |