Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9654632 | 1.00 | ALDH1A1 (0.37) | ALDH1A1MEN1MAPTKMT2ARXFP1 | |
| Dimethylcarbate SCHEMBL9679433 | 0.88 | ALDH1A1 (0.37) | ALDH1A1MEN1MAPTKMT2ARXFP1 | |
| Dimethylcarbate SCHEMBL9679440 | 0.88 | ALDH1A1 (0.37) | ALDH1A1MEN1MAPTKMT2ARXFP1 | |
| SCHEMBL9017850 | 0.84 | ALDH1A1 (0.35) | ALDH1A1MEN1MAPTKMT2ARXFP1 | |
| SCHEMBL9017856 | 0.84 | ALDH1A1 (0.35) | ALDH1A1MEN1MAPTKMT2ARXFP1 | |
| SCHEMBL9679510 | 0.83 | KDM5A (0.34) | ALDH1A1MEN1MAPTKMT2ARXFP1 | |
| SCHEMBL9679504 | 0.83 | KDM5A (0.34) | ALDH1A1MEN1MAPTKMT2ARXFP1 | |
| SCHEMBL9017887 | 0.83 | P2RX4 (0.33) | ALDH1A1MEN1MAPTKMT2ARXFP1 | |
| SCHEMBL9679926 | 0.82 | ALDH1A1 (0.36) | ALDH1A1MEN1MAPTKMT2ARXFP1 | |
| SCHEMBL9679933 | 0.82 | ALDH1A1 (0.36) | ALDH1A1MEN1MAPTKMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477903-A2 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-04-01 | — | — | EP | disclosed |