SCHEMBL9680049

SCHEMBL9680049

Cc1ccc(C(=O)Oc2ccc3c(c2)C(=O)OC3=O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 11/20 0.56
GBA1 P04062 1/20 0.56
LMNA P02545 1/20 0.50
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49
GAA P10253 2/20 0.47
HPGD P15428 1/20 0.47
PRSS1 P07477 1/20 0.47
ACR P10323 1/20 0.47
FNTA P49354 1/20 0.46
FNTB P49356 1/20 0.46
MAPT P10636 4/20 0.46
MEN1 O00255 3/20 0.46
HSD17B10 Q99714 1/20 0.46
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
ALDH1A1 P00352 3/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA4 P22748 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29426396 0.92 KMT2A (0.51) KMT2AGBA1GAAMAPTMEN1
SCHEMBL4204276 0.92 KMT2A (0.51) KMT2AGBA1GAAMAPTMEN1
SCHEMBL31124167 0.88 KMT2A (0.47) KMT2AFNTAFNTBMAPTMEN1
SCHEMBL31124079 0.88 KMT2A (0.47) KMT2AFNTAFNTBMAPTMEN1
SCHEMBL4598444 0.88 KMT2A (0.47) KMT2AFNTAFNTBMAPTMEN1
SCHEMBL9680648 0.86 KMT2A (0.59) KMT2AGAAMAPTMEN1HSD17B10
SCHEMBL8968025 0.86 KMT2A (0.48) KMT2ACYP2C9MAPTMEN1HSD17B10
SCHEMBL9681102 0.85 MAPT (0.60) KMT2ACYP1A2CYP2C9MAPTMEN1
SCHEMBL23039676 0.84 PARP10 (0.47) KMT2APRSS1FNTAFNTBMAPT
SCHEMBL30872886 0.84 PARP10 (0.47) KMT2APRSS1FNTAFNTBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5153335-A Reacting halophthalic anhydride and alkali metal salt with acid or acid derivative catalyst OCCIDENTAL CHEMICAL CORPORATION (US) 1992-10-06 US claimed
EP-0460687-A2 Process for the preparation of oxydiphthalic anhydride and acyloxyphthalic anhydrides OCCIDENTAL CHEMICAL CORPORATION (US) 1991-12-11 EP claimed
US-5153335-A Reacting halophthalic anhydride and alkali metal salt with acid or acid derivative catalyst OCCIDENTAL CHEMICAL CORPORATION (US) 1992-10-06 US disclosed
EP-0460687-A2 Process for the preparation of oxydiphthalic anhydride and acyloxyphthalic anhydrides OCCIDENTAL CHEMICAL CORPORATION (US) 1991-12-11 EP disclosed