SCHEMBL8968025

SCHEMBL8968025

O=C(Oc1ccc2c(c1)C(=O)OC2=O)c1cc(C(=O)Oc2ccc3c(c2)C(=O)OC3=O)cc(C(=O)Oc2ccc3c(c2)C(=O)OC3=O)c1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.48
MAPT P10636 6/20 0.48
MEN1 O00255 4/20 0.48
HSD17B10 Q99714 1/20 0.48
GRM5 P41594 1/20 0.46
CA9 Q16790 3/20 0.46
CA12 O43570 2/20 0.46
PTGES O14684 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
MAOA P21397 2/20 0.44
MAOB P27338 2/20 0.44
POLB P06746 1/20 0.43
ALDH1A1 P00352 2/20 0.42
CYP2C9 P11712 1/20 0.42
USP2 O75604 1/20 0.41
BCL2L1 Q07817 1/20 0.41
MCL1 Q07820 1/20 0.41
CA2 P00918 1/20 0.41
NSD2 O96028 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4990373 0.93 KMT2A (0.49) KMT2AMAPTMEN1HSD17B10GRM5
SCHEMBL4204276 0.93 KMT2A (0.51) KMT2AMAPTMEN1HSD17B10GRM5
SCHEMBL29426396 0.93 KMT2A (0.51) KMT2AMAPTMEN1HSD17B10GRM5
SCHEMBL31124167 0.92 KMT2A (0.47) KMT2AMAPTMEN1HSD17B10GRM5
SCHEMBL4598444 0.92 KMT2A (0.47) KMT2AMAPTMEN1HSD17B10GRM5
SCHEMBL31124079 0.92 KMT2A (0.47) KMT2AMAPTMEN1HSD17B10GRM5
SCHEMBL9680648 0.90 KMT2A (0.59) KMT2AMAPTMEN1HSD17B10GRM5
SCHEMBL9680737 0.89 MAOA (0.47) KMT2AMAPTMEN1HSD17B10GRM5
SCHEMBL29363037 0.86 CA2 (0.47) KMT2AMAPTMEN1HSD17B10GRM5
SCHEMBL30693355 0.86 CA2 (0.47) KMT2AMAPTMEN1HSD17B10GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5571579-A FORMING A POLYIMIDE FILM AND RUBBING THE SURFACE OF THE FILM HITACHI CHEMICAL COMPANY, LTD (JP) 1996-11-05 US disclosed