⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2704009 | 0.97 | CYP1A2 (0.42) | — | |
| SCHEMBL911042 | 0.97 | CYP1A2 (0.42) | — | |
| SCHEMBL5218136 | 0.94 | — | — | |
| SCHEMBL98082 | 0.88 | — | — | |
| SCHEMBL2076620 | 0.84 | CYP1A2 (0.46) | — | |
| SCHEMBL99022 | 0.82 | CYP1A2 (0.50) | — | |
| SCHEMBL8390897 | 0.82 | CYP1A2 (0.50) | — | |
| SCHEMBL7350448 | 0.80 | SIGMAR1 (0.50) | — | |
| SCHEMBL97094 | 0.80 | SIGMAR1 (0.50) | — | |
| SCHEMBL1335898 | 0.80 | SIGMAR1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 619 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999237-B | Nucleoside prodrug and application thereof | 润佳（苏州）医药科技有限公司 | 2023-08-08 | — | — | CN | claimed |
| EP-2755983-B1 | SUBSTITUTED CARBONYLOXYMETHYLPHOSPHORAMIDATE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS | IDENIX PHARMACEUTICALS LLC (US) | 2017-03-15 | — | — | EP | claimed |
| US-8357675-B2 | 17-alpha-substituted derivatives of estradiol with wound-healing activity | EUTICALS S.P.A. (IT) | 2013-01-22 | — | — | US | claimed |
| US-8273740-B2 | antiallergen; not direct way to change nature of immunological response to allergen; G-protein-coupled \"chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2)\" antagonist for prostaglandin PGD2, that mediates PGD2-dependent migration of blood Th2 cells; ; asthma, rhinitis, COPD | ACTELION PHARMACEUTICALS, LTD. (CH) | 2012-09-25 | — | — | US | claimed |
| US-8034936-B2 | Spirocyclic cyclohexane compounds useful to treat substance dependency | GRUENENTHAL GMBH (DE) | 2011-10-11 | — | — | US | claimed |
| US-20110053970-A1 | Spirocyclic Cyclohexane Compounds Useful To Treat Substance Dependency | GRUENENTHAL GMBH (DE) | 2011-03-03 | — | — | US | claimed |
| US-20100234396-A1 | Tetrhydropyridoindole Derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2010-09-16 | — | — | US | claimed |
| CN-1930162-B | Tetrahydropyridoindole derivatives | ACTELION PHARMACEUTICALS LTD | 2010-06-16 | — | — | CN | claimed |
| US-20100081708-A1 | ANTICOAGULANT COMPOUNDS | ENDOTIS PHARMA (FR) | 2010-04-01 | — | — | US | claimed |
| EP-2074131-A2 | ANTICOAGULANT COMPOUNDS | Endotis Pharma (FR) | 2009-07-01 | — | — | EP | claimed |
| WO-1998034115-A1 | 4-SUBSTITUTED-QUINOLINE DERIVATIVES AND 4-SUBSTITUTE-QUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | claimed |
| US-4918056-A | ANTITUMOR AGENTS | HEALTH RESEARCH, INC. (ROSWELL PARK DIVISION) (US) | 1990-04-17 | — | — | US | claimed |
| EP-0187052-B1 | ADAMANTAN AMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | S.A. PANMEDICA Société dite: (FR) | 1990-01-31 | — | — | EP | claimed |
| US-4661512-A | Adamantanamine derivatives, processes for their preparation and drugs in which they are present | S. A. PANMEDICA (FR) | 1987-04-28 | — | — | US | claimed |
| EP-0187052-A1 | Adamantan amine derivatives, process for their preparation and medicines containing them | S.A. PANMEDICA Société dite: (FR) | 1986-07-09 | — | — | EP | claimed |
| EP-0030299-B1 | STEROID ESTERS OF METHYLATED PROSTAGLANDIN DERIVATIVES AND THEIR PHARMACEUTICAL COMPOSITIONS | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-01-16 | — | — | EP | claimed |
| US-4321366-A | Process of preparing 2-azido-2-deoxyarabinofuranosyl halides | RESEARCH CORPORATION (US) | 1982-03-23 | — | — | US | claimed |
| US-4318908-A | Methylated prostaglandin derivatives | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-03-09 | — | — | US | claimed |
| EP-0030299-A1 | Steroid esters of methylated prostaglandin derivatives and their pharmaceutical compositions | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1981-06-17 | — | — | EP | claimed |
| US-4230698-A | ANTITUMOR AGENTS, VIRICIDES, AND MICROBIOCIDES | RESEARCH CORPORATION (US) | 1980-10-28 | — | — | US | claimed |