SCHEMBL9680241

SCHEMBL9680241

C=C(C)C(=O)OCC(C(F)(F)F)C(F)(F)F

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.59
THRB P10828 1/20 0.41
ALDH1A1 P00352 2/20 0.39
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28039559 0.89 TSHR (0.52) TSHRTHRBALDH1A1
SCHEMBL16605509 0.85 TSHR (0.47) TSHRTHRBALDH1A1
SCHEMBL9551843 0.84 TSHR (0.59) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL21123180 0.82 TSHR (0.62) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL9356678 0.82 TSHR (0.57) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL10454150 0.82 TSHR (0.36) TSHRHTT
SCHEMBL27701673 0.81 THRB (0.47) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL18560051 0.80 TSHR (0.35) TSHR
SCHEMBL13533495 0.79 TSHR (0.53) TSHRTHRBALDH1A1
SCHEMBL9650012 0.79 TSHR (0.53) TSHRTHRBALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111501325-A Surface-wrinkled fiber material and preparation method thereof 东华大学 2020-08-07 CN claimed
CN-1296440-C Transparent ultrauiolet cured coating and preparing method thereof HUIYUAN OPTICAL COMM CO LTD SI (CN) 2007-01-24 CN claimed
CN-1243258-C Plastic optical fiber containing ultraviolet-light solidifying coating cladding and preparation method HUIYUANG OPTICAL COMM CO LTD S (CN) 2006-02-22 CN claimed
CN-1528831-A Transparent ultrauiolet cured coating and preparing method thereof 四川汇源光通信股份有限公司 2004-09-15 CN claimed
CN-1529189-A Plastic optical fiber containing ultraviolet-light solidifying coating cladding and preparation method 四川汇源光通信股份有限公司 2004-09-15 CN claimed
US-4779954-A CORE OF DEUTERATED METHYL METHACRYLATE POLYMER AND CLADDING OF TRANSPARENT POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-10-25 US claimed
EP-0144712-B1 OPTICAL FIBER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-03-30 EP claimed
EP-0144712-A2 Optical fiber SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-06-19 EP claimed
CN-111501325-B Surface-wrinkled fiber material and preparation method thereof 东华大学 2021-09-17 CN disclosed
CN-111501325-A Surface-wrinkled fiber material and preparation method thereof 东华大学 2020-08-07 CN disclosed
US-9760010-B2 Patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-09-12 US disclosed
EP-1415974-B1 PROCESS FOR PRODUCTION OF FLUORINE-CONTAINING NORBORNENE DERIVATIVES DAIKIN IND LTD (JP) 2017-03-01 EP disclosed
CN-103483853-B Hardening resin composition 小西株式会社 2017-03-01 CN disclosed
US-20160363866-A1 PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-12-15 US disclosed
CN-1529189-A Plastic optical fiber containing ultraviolet-light solidifying coating cladding and preparation method 四川汇源光通信股份有限公司 2004-09-15 CN disclosed
US-5113477-A Core, cladding, heat resistance HITACHI, LTD. (JP) 1992-05-12 US disclosed
US-4779954-A CORE OF DEUTERATED METHYL METHACRYLATE POLYMER AND CLADDING OF TRANSPARENT POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-10-25 US disclosed
EP-0144712-B1 OPTICAL FIBER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-03-30 EP disclosed
EP-0226020-A2 Plastic optical fibers and transparent resin used therefor HITACHI, LTD. (JP) 1987-06-24 EP disclosed
EP-0144712-A2 Optical fiber SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-06-19 EP disclosed