Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.70 |
| ▸ | MEN1 | O00255 | 9/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679742 | 0.81 | KMT2A (0.60) | KMT2AMEN1TDP1 | |
| SCHEMBL25681698 | 0.80 | KMT2A (0.82) | KMT2AMEN1TDP1ALDH1A1LMNA | |
| SCHEMBL9680704 | 0.78 | KMT2A (0.72) | KMT2AMEN1TDP1 | |
| SCHEMBL25681470 | 0.77 | KMT2A (0.63) | KMT2AMEN1TDP1ALDH1A1LMNA | |
| SCHEMBL9681089 | 0.77 | KMT2A (0.57) | KMT2AMEN1TDP1LMNA | |
| SCHEMBL9679661 | 0.75 | KMT2A (0.77) | KMT2AMEN1TDP1ALDH1A1LMNA | |
| SCHEMBL5797214 | 0.75 | MEN1 (0.51) | KMT2AMEN1 | |
| SCHEMBL9754199 | 0.74 | ALDH1A1 (0.53) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL9678877 | 0.74 | TDP1 (0.58) | KMT2AMEN1TDP1ALDH1A1LMNA | |
| SCHEMBL9679252 | 0.73 | KMT2A (0.66) | KMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | claimed |
| US-5153226-A | Administering as anticholesterol agents, for atherosclerosis | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |