Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 2/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylcarbate SCHEMBL9680344 | 1.00 | KDM6B (0.34) | KDM6BKDM4CHCAR3NAMPTSLC6A2 | |
| SCHEMBL9679870 | 0.91 | — | — | |
| SCHEMBL9679866 | 0.91 | — | — | |
| Dimethylcarbate SCHEMBL9681182 | 0.91 | MAPT (0.36) | KDM6BKDM4C | |
| Dimethylcarbate SCHEMBL9681187 | 0.91 | MAPT (0.36) | KDM6BKDM4C | |
| Dimethylcarbate SCHEMBL9679433 | 0.85 | ALDH1A1 (0.37) | KDM6BKDM4C | |
| Dimethylcarbate SCHEMBL9679440 | 0.85 | ALDH1A1 (0.37) | KDM6BKDM4C | |
| SCHEMBL9017925 | 0.81 | MAPT (0.35) | — | |
| SCHEMBL9017872 | 0.80 | MAPT (0.32) | — | |
| SCHEMBL9017876 | 0.80 | MAPT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477903-A2 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-04-01 | — | — | EP | disclosed |