Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.36 |
| ▸ | PDE2A | O00408 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 2/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10552867 | 0.78 | LMNA (0.50) | LMNAKMT2APDE3BPDE3APDE2A | |
| SCHEMBL9677526 | 0.77 | LMNA (0.54) | LMNAKMT2APDE3BPDE3APDE2A | |
| SCHEMBL9679604 | 0.77 | LMNA (0.43) | LMNAKMT2APDE3BPDE3APDE2A | |
| SCHEMBL4918102 | 0.76 | METAP1 (0.49) | KMT2ANPC1RAB9AATMERAP1 | |
| SCHEMBL4952422 | 0.76 | AURKA (0.52) | LMNAKMT2APDE3BPDE3APDE2A | |
| SCHEMBL10551194 | 0.76 | LMNA (0.48) | LMNAKMT2APDE3BPDE3APDE2A | |
| SCHEMBL10551686 | 0.76 | LMNA (0.48) | LMNAKMT2APDE3BPDE3APDE2A | |
| SCHEMBL9677425 | 0.75 | LMNA (0.43) | LMNAKMT2APDE3BPDE3APDE2A | |
| SCHEMBL10553469 | 0.75 | LMNA (0.43) | LMNAKMT2APDE3BPDE3APDE2A | |
| SCHEMBL10556108 | 0.74 | LMNA (0.49) | LMNAKMT2APDE3BPDE3APDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207483-B1 | BENZIMIDAZOLES, PROCESS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM AND INTERMEDIATES | Roche Diagnostics GmbH (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-4831032-A | CARDIOVASCULAR DISORDERS, HYPOTENSIVE, ISOTROPIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-05-16 | — | — | US | disclosed |
| EP-0248554-A2 | Heterocyclic compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-12-09 | — | — | EP | disclosed |
| EP-0228788-A1 | Herbicidal derivatives of substituted benzoyl-hydrazinium compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-07-15 | — | — | EP | disclosed |
| EP-0229034-A2 | Hexopyranoses and compositions for agricultural use | HER MAJESTY THE QUEEN in right of New Zealand Department of Scientific and Industrial Research (NZ) | 1987-07-15 | — | — | EP | disclosed |
| EP-0207483-A2 | Benzimidazoles, process for their preparation, medicaments containing them and intermediates | Roche Diagnostics GmbH (DE) | 1987-01-07 | — | — | EP | disclosed |
| EP-0124985-A1 | Herbicidal diphenyl ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-14 | — | — | EP | disclosed |
| EP-0122037-A1 | Substituted diphenylether compounds useful as herbicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-10-17 | — | — | EP | disclosed |
| EP-0085530-A2 | Cyclohexane dione derivatives, their use as herbicides, herbicidal compositions containing them, and methods of preparing them | ICI AUSTRALIA LIMITED (AU) | 1983-08-10 | — | — | EP | disclosed |
| EP-0080301-A2 | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1983-06-01 | — | — | EP | disclosed |
| EP-0063866-A1 | Quinolin-3-yloxy(amino)phenoxyalkane carboxylic acid derivatives, process for their synthesis, herbicidal compositions containing them, and their use as herbicides | ICI AUSTRALIA LIMITED (AU) | 1982-11-03 | — | — | EP | disclosed |
| EP-0026622-A2 | Quinoxalinylaminophenoxyalkane carboxylic acid derivatives, their preparation, their use as herbicides and intermediates | ICI AUSTRALIA LIMITED (AU) | 1981-04-08 | — | — | EP | disclosed |
| EP-0024932-A2 | 1,2,4-Benzotriazinyloxyphenoxyalkane carboxylic-acid derivatives, processes for their preparation, their use as herbicides, and their preparation | ICI AUSTRALIA LIMITED (AU) | 1981-03-11 | — | — | EP | disclosed |
| EP-0024931-A2 | 1,2,4-Benzotriazinylaminophenoxyalkane carboxylic acid derivatives, processes for their preparation and their use as herbicides | ICI AUSTRALIA LIMITED (AU) | 1981-03-11 | — | — | EP | disclosed |
| EP-0023785-A2 | Quinoxalinyloxyphenoxyalkane carboxylic acid derivatives, their preparation and their use as herbicides | ICI AUSTRALIA LIMITED (AU) | 1981-02-11 | — | — | EP | disclosed |
| EP-0013144-A1 | Substituted diphenylamine derivatives, compositions and herbicidal uses thereof, and processes for their preparation | ICI AUSTRALIA LIMITED (AU) | 1980-07-09 | — | — | EP | disclosed |