SCHEMBL9680443

SCHEMBL9680443

CC(=O)OCCN(C)c1ccc(C=O)cc1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.46
CYP2A13 Q16696 1/20 0.46
ALDH1A1 P00352 7/20 0.43
ALDH3A1 P30838 1/20 0.43
ALDH1A3 P47895 1/20 0.43
RAD52 P43351 1/20 0.40
KMT2A Q03164 1/20 0.35
PPARG P37231 1/20 0.33
HSD17B3 P37058 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3038631 0.88 CYP2A6 (0.41) CYP2A6CYP2A13ALDH1A1ALDH3A1ALDH1A3
SCHEMBL7987478 0.86 ALDH1A1 (0.53) CYP2A6CYP2A13ALDH1A1ALDH3A1ALDH1A3
SCHEMBL278891 0.85 CYP2A6 (0.41) CYP2A6CYP2A13ALDH1A1ALDH3A1ALDH1A3
SCHEMBL10386780 0.84 CYP2A6 (0.42) CYP2A6CYP2A13ALDH1A1ALDH3A1ALDH1A3
SCHEMBL5689109 0.83 ALDH1A1 (0.59) CYP2A6CYP2A13ALDH1A1ALDH3A1ALDH1A3
SCHEMBL13456623 0.80 ALDH1A1 (0.41) CYP2A6CYP2A13ALDH1A1ALDH3A1ALDH1A3
SCHEMBL12455661 0.80 ALDH1A1 (0.41) CYP2A6CYP2A13ALDH1A1ALDH3A1ALDH1A3
SCHEMBL18692778 0.80 CYP2A6 (0.52) CYP2A6CYP2A13ALDH1A1ALDH3A1ALDH1A3
SCHEMBL3036233 0.80 RAD52 (0.51) ALDH1A1RAD52PPARGLMNASMN1; SMN2
SCHEMBL13645995 0.79 CYP2A6 (0.64) CYP2A6CYP2A13ALDH1A1ALDH3A1ALDH1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0464904-A2 An optical article exhibiting a high level of second order polarization susceptibility EASTMAN KODAK COMPANY (US) 1992-01-08 EP disclosed
US-5029979-A Optical article exhibiting a high level of second order polarization susceptibility EASTMAN KODAK COMPANY (US) 1991-07-09 US disclosed
US-4513142-A Preparation of cationic methine dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1985-04-23 US disclosed
EP-0074569-A2 Cationic methine dyes, process for their preparation and their use, in dyeing textile materials and other substrates BAYER AG (DE) 1983-03-23 EP disclosed